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ONLINEISSN:1347-5223
PRINTISSN:0009-2363
CHEMICAL & PHARMACEUTICAL BULLETIN
Vol. 54 (2006) , No. 11


Review

Trace Determination of Steroids Causing Age-Related Diseases Using LC/MS Combined with Detection-Oriented Derivatization1479
Tatsuya Higashi
Release Date: 2006/11/01
[Abstract] [PDF (362K)


Regular Articles

Particle Design of Three-Component System for Sustained Release Using a 4-Fluid Nozzle Spray-Drying Technique1486
Richer Chen, Hirokazu Takahashi, Hirokazu Okamoto and Kazumi Danjo
Release Date: 2006/11/01
[Abstract] [PDF (385K)

Comparative Study of Chemical Constituents of Rhubarb from Different Origins1491
Katsuko Komatsu, Yorinobu Nagayama, Ken Tanaka, Yun Ling, Shao-Qing Cai, Takayuki Omote and Meselhy Ragab Meselhy
Release Date: 2006/11/01
[Abstract] [PDF (816K)

Optimization and Physicochemical Characterization of Thermosensitive Poloxamer Gel Containing Puerarin for Ophthalmic Use1500
Hongyi Qi, Li Li, Chunyan Huang, Wenmin Li and Chunjie Wu
Release Date: 2006/11/01
[Abstract] [PDF (969K)

Novel Approach to DPI Carrier Lactose with Mechanofusion Process with Additives and Evaluation by IGC1508
Michiko Kumon, Masahiko Suzuki, Akira Kusai, Etsuo Yonemochi and Katsuhide Terada
Release Date: 2006/11/01
[Abstract] [PDF (1754K)

4-(Pyrrolidinyl)methoxybenzoic Acid Derivatives as a Potent, Orally Active VLA-4 Antagonist1515
Jun Chiba, Shin Iimura, Yoshiyuki Yoneda, Yuichi Sugimoto, Takao Horiuchi, Fumito Muro, Yuichi Ochiai, Tomomi Ogasawara, Masao Tsubokawa, Yutaka Iigou, Gensuke Takayama, Tomoe Taira, Yoshimi Takata, Mika Yokoyama, Tohru Takashi, Atsushi Nakayama and Nobuo Machinaga
Release Date: 2006/11/01
[Abstract] [PDF (427K)

Structures of New Flavonoids, Erycibenins D, E, and F, and NO Production Inhibitors from Erycibe expansa Originating in Thailand1530
Toshio Morikawa, Fengming Xu, Hisashi Matsuda and Masayuki Yoshikawa
Release Date: 2006/11/01
[Abstract] [PDF (199K)

Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as Factor Xa Inhibitors V. A Series of New Derivatives Containing a Spiro[imidazo[1,2-a]pyrazine-2(3H),4′-piperidin]-5(1H)-one Scaffold1535
Fumihiko Saitoh, Takafumi Mukaihira, Hidemitsu Nishida, Tsutomu Satoh, Akihiro Okano, Yasunobu Yumiya, Munetaka Ohkouchi, Rumi Johka, Tomokazu Matsusue, Ikuya Shiromizu, Yoshitaka Hosaka, Miwa Matsumoto and Shuhei Ohnishi
Release Date: 2006/11/01
[Abstract] [PDF (326K)

Structures of New Cucurbitane-Type Triterpenes and Glycosides, Karavilagenins and Karavilosides, from the Dried Fruit of Momordica charantia L. in Sri Lanka1545
Seikou Nakamura, Toshiyuki Murakami, Junko Nakamura, Hisanori Kobayashi, Hisashi Matsuda and Masayuki Yoshikawa
Release Date: 2006/11/01
[Abstract] [PDF (323K)

Glycosides of 14,15-Seco and 13,14:14,15-Disecopregnanes from the Roots of Cynanchum sublanceolatum1551
Tsutomu Warashina and Tadataka Noro
Release Date: 2006/11/01
[Abstract] [PDF (232K)

Solubility Prediction of Drugs in Water–Polyethylene Glycol 400 Mixtures Using Jouyban–Acree Model1561
Abolghasem Jouyban
Release Date: 2006/11/01
[Abstract] [PDF (204K)

Synthesis and Anti-tumor Activity of a Fluorinated Analog of Medroxyprogesterone Acetate (MPA), 9α-Fluoromedroxyprogesterone Acetate (FMPA)1567
Natsuko Murata, Shiho Fujimori, Yoshitatsu Ichihara, Yoshio Sato, Taketo Yamaji, Hiroshi Tsuboi, Masayuki Uchida, Hiroto Suzuki, Masashi Yamada, Tsutomu Oikawa, Hideo Nemoto, Junko Nobuhiro, Tominari Choshi and Satoshi Hibino
Release Date: 2006/11/01
[Abstract] [PDF (183K)

Oxidative Photo-Decarboxylation in the Presence of Mesoporous Silicas1571
Akichika Itoh, Tomohiro Kodama, Yukio Masaki and Shinji Inagaki
Release Date: 2006/11/01
[Abstract] [PDF (165K)

Function of an N-Heterocyclic Carbene Ligand Based on Concept of Chiral Mimetic1576
Takafumi Arao, Kei Sato, Kazuhiro Kondo and Toyohiko Aoyama
Release Date: 2006/11/01
[Abstract] [PDF (200K)

Xylogranatins A—D, New Mexicanolides from the Fruit of a Chinese Mangrove Xylocarpus granatum1582
Jun Wu, Si Zhang, Minyi Li, Yuan Zhou and Qiang Xiao
Release Date: 2006/11/01
[Abstract] [PDF (320K)


Notes

Quantitative Structure–Activity Relationships of Selective Antagonists of Glucagon Receptor Using QuaSAR Descriptors1586
Palanivelu Manoj Kumar, Chandrabose Karthikeyan, Narayana Subbiah Hari Narayana Moorthy and Piyush Trivedi
Release Date: 2006/11/01
[Abstract] [PDF (197K)

Hepatitis B Virus Inhibiting Constituents from Herpetospermum caudigerum1592
Hai-Long Yuan, Ming Yang, Xian-Yi Li, Rong-Hui You, Yi Liu, Jun Zhu, Huan Xie and Xiao-He Xiao
Release Date: 2006/11/01
[Abstract] [PDF (93K)

Sesquiterpene Coumarins from the Roots of Ferula sinkiangensis and Ferula teterrima1595
Jun-Rong Yang, Zheng An, Zhi-Hong Li, Song Jing and Hai-Lin Qina
Release Date: 2006/11/01
[Abstract] [PDF (179K)

New Sesquiterpene Lactones from the Aerial Parts of Pseudoelephantopus spicatus1599
Hamad Hassan Issa, Sue-Ming Chang, Yu-Liang Yang, Fang-Rong Chang and Yang-Chang Wu
Release Date: 2006/11/01
[Abstract] [PDF (158K)

Semisynthesis of Isetexane Diterpenoid Analogues and Their Cytotoxic Activity1602
Yutaka Aoyagi, Yoshinao Takahashi, Haruhiko Fukaya, Koichi Takeya, Ritsuo Aiyama, Takeshi Matsuzaki, Shusuke Hashimoto and Teruo Kurihara
Release Date: 2006/11/01
[Abstract] [PDF (105K)

Cucurbitacin B 2-Sulfate and Cucurbitacin Glucosides from the Root Bark of Helicteres angustifolia1605
Zong-Tsi Chen, Shwu-Woan Lee and Chiu-Ming Chen
Release Date: 2006/11/01
[Abstract] [PDF (81K)

A Facile and Clean Direct Cyanation of Heteroaromatic Compounds Using a Recyclable Hypervalent Iodine(III) Reagent1608
Toshifumi Dohi, Koji Morimoto, Naoko Takenaga, Akinobu Maruyama and Yasuyuki Kita
Release Date: 2006/11/01
[Abstract] [PDF (79K)

Scandium-Catalyzed Carbon–Carbon Bond Formations Using α-Organosulfanyl and Organoselanyl-α-fluoroacetic Acid Derivatives1611
Kohei Gotoh, Teruhisa Yamamoto and Mitsuhiro Yoshimatsu
Release Date: 2006/11/01
[Abstract] [PDF (148K)

Efficient Synthesis of Isothiocyanates Based on the Tandem Staudinger/aza-Wittig Reactions and Mechanistic Consideration of the Tandem Reactions1616
Takeshi Isoda, Kazuhiko Hayashi, Satoshi Tamai, Toshio Kumagai and Yoshimitsu Nagao
Release Date: 2006/11/01
[Abstract] [PDF (123K)


Communications to the Editor

Aerobic Oxidation of Benzyl- and Allylic Alcohols under Visible Light Irradiation of a Fluorescent Lamp in the Presence of Catalytic Iodine1620
Hiroki Nakayama and Akichika Itoh
Release Date: 2006/11/01
[Abstract] [PDF (92K)

Dirhodium(II) Tetrakis(perfluorobutyrate)-Catalyzed 1,4-Hydrosilylation of α,β-Unsaturated Carbonyl Compounds1622
Masahiro Anada, Masahiko Tanaka, Kanami Suzuki, Hisanori Nambu and Shunichi Hashimoto
Release Date: 2006/11/01
[Abstract] [PDF (99K)



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